Supplements After Menopause: Comparing 8 Brands for Muscle, Bone, and Skin Nutrition

Woman in her late 50s reading an AgelessLX Strawberry Lemonade stick pack at a kitchen island with the AgelessLX pouch and unbranded supplement bottles

AgelessLX, Life Extension, Metagenics, Nature Made, NOW Sports, Pure Encapsulations, Thorne, and Vital Proteins provide different types of products to compare for muscle, bone, and skin-related nutrition. Start with the type of product you are looking for, then compare its complete label with your usual diet and existing supplements.

This guide covers HMB combinations, calcium and vitamin formulas, multivitamins, protein powder, and collagen powder. They serve different nutritional purposes and are not interchangeable. The comparison describes product information without ranking health outcomes.

Disclosure: NourigenLabs publishes this article and sells AgelessLX. AgelessLX references are promotional and marked [Sponsored]. Product information reviewed October 28, 2026. AgelessLX is listed first; the other brands follow alphabetically.

Eight Brands and the Products Being Compared

The table names one product or product format for each brand. Its final column explains what to compare on the label, rather than claiming that one brand is better. Product names link directly to official sources.

Brand and official product Comparison category What to check
AgelessLX [Sponsored]
Strawberry Lemonade
HMB combination One 5.7 g stick lists HMB 3,000 mg, calcium 450 mg, vitamins D and K, biotin, and horsetail.
Life Extension
Bone Restore with Vitamin K2
Bone nutrient formula Four capsules list calcium 700 mg, vitamin D3 25 mcg, vitamin K2 200 mcg, and magnesium 300 mg.
Metagenics
Bone Builder
Calcium and phosphorus formula Three tablets list calcium 620 mg, phosphorus 360 mg, and MCHC 1.5 g.
Nature Made
Calcium 600 mg with Vitamin D3
Calcium and vitamin D One tablet lists calcium 600 mg and vitamin D3 10 mcg. Directions: one tablet one to two times daily.
NOW Sports
Whey Protein Isolate, Creamy Vanilla
Protein powder One level 32 g scoop lists 25 g protein. Contains milk; also includes xylitol and stevia.
Pure Encapsulations
Calcium K/D
Calcium with vitamins D and K The linked product sheet lists calcium 400 mg, vitamin D3 25 mcg, K1 100 mcg, and K2 30 mcg per two capsules.
Thorne
Basic Nutrients 2/Day
Multivitamin and mineral formula Two capsules list vitamin D3 50 mcg, K1 200 mcg, K2 (MK-4) 200 mcg, and biotin 500 mcg.
Vital Proteins
Collagen Peptides, Unflavored
Collagen powder The selected 10 oz label lists 20 g bovine collagen peptides and 18 g protein per 20 g serving.

These are product categories for comparison, not a recommendation to take all eight products together. Not every product is designed specifically for postmenopausal women.

Choose the Nutritional Question Before the Brand

Are you comparing HMB products or protein powders?

HMB supplements and protein powders belong to different product categories. Check the label for the ingredient you intend to buy. An HMB amount in milligrams is not a substitute for the protein grams shown on a protein-powder label.

For example, NOW Sports’ Creamy Vanilla Whey Protein Isolate lists 25 g protein per serving. AgelessLX Strawberry Lemonade has a different Supplement Facts panel built around HMB and other named ingredients. Compare each within the category relevant to your question.

Are you comparing bone-related nutrients?

Start by comparing the amounts and forms of calcium and vitamins on each label. Life Extension, Metagenics, Nature Made, and Pure Encapsulations have different combinations. A product name containing “bone” does not mean the formulas or daily servings are equivalent.

Review your food intake and existing supplements with a healthcare professional before adding another mineral or vitamin product. Avoid treating every ingredient in a combination formula as an extra amount you need.

Are you comparing collagen or other skin-related ingredients?

Collagen Peptides is a collagen powder, while an HMB combination or multivitamin may include biotin and other ingredients. Read the actual ingredient panel rather than relying on a beauty or healthy-aging category name.

NIH reports that evidence supporting biotin supplements for skin, hair, and nail claims is limited. The presence of biotin on a label does not establish a visible result for an individual.

A Closer Look at the Eight Options

Life Extension: Bone Restore with Vitamin K2

Life Extension’s Bone Restore with Vitamin K2 lists, per four-capsule serving, calcium 700 mg, vitamin D3 25 mcg, vitamin K2 (MK-7) 200 mcg, and magnesium 300 mg, plus other nutrients. The 120-capsule bottle contains 30 servings; directions specify four capsules daily. Compare this capsule formula with any calcium, vitamin D, or multivitamin product already in your routine.

Metagenics: Bone Builder

Bone Builder lists 620 mg calcium, 360 mg phosphorus, and 1.5 g microcrystalline hydroxyapatite concentrate (MCHC) per three tablets. Calcium and phosphorus are supplied as MCHC and dicalcium phosphate. Directions specify three tablets once daily. Do not add the separately declared MCHC weight to the calcium amount.

Nature Made: Calcium 600 mg with Vitamin D3

The selected Nature Made product lists 600 mg calcium and 10 mcg vitamin D3 per tablet. The official directions specify one tablet one to two times daily with water and a meal. Keep the per-tablet amount separate from the daily intake you discuss with your healthcare professional.

NOW Sports: Whey Protein Isolate

The Creamy Vanilla formula lists 25 g protein per level 32 g scoop. Directions specify one scoop daily in 8 fl oz of cold water, milk, or juice. The ingredients include whey protein isolate, xylitol, natural vanilla flavors, xanthan gum, stevia, and sunflower lecithin; the label declares milk. This is a protein powder, not an HMB or mineral formula.

Pure Encapsulations: Calcium K/D

Calcium K/D combines di-calcium malate with vitamins D3, K1, and K2. The product information sheet currently linked by the manufacturer (dated April 2021) lists, per two capsules, calcium 400 mg, vitamin D3 25 mcg, vitamin K1 100 mcg, and vitamin K2 (MK-7) 30 mcg. Directions specify two capsules one to three times daily with meals. Confirm these figures against the current bottle label before purchase.

Thorne: Basic Nutrients 2/Day

Basic Nutrients 2/Day is a multivitamin and mineral formula. Its two-capsule serving lists vitamin D3 50 mcg, vitamin K1 200 mcg, vitamin K2 (MK-4) 200 mcg, biotin 500 mcg, and calcium 52 mg, among other nutrients. The selected 60-capsule bottle provides 30 servings. Review the whole panel before combining it with a focused calcium or vitamin product.

Vital Proteins: Collagen Peptides

The unflavored Collagen Peptides product uses bovine collagen. The selected 10 oz label lists 20 g collagen peptides and 18 g protein per four-tablespoon (20 g) serving, with about 14 servings per container. Directions specify four level tablespoons in total per day. Collagen grams and protein grams are separate label entries; this collagen powder is not interchangeable with whey protein or a multivitamin.

Check Serving Sizes, Ingredient Overlap, and Purchase Terms

Compare specific products, not whole brands. Use the same units, the selected label’s serving size, and its daily directions. Different product categories do not provide a meaningful comparison simply by price per capsule.

Comparison step Practical check
Identify the product Record the exact name, flavor, and package size.
Read the daily directions Separate the amount in one serving from the amount used in a full day.
Check ingredient overlap Review repeated vitamins and minerals across all products you take.
Compare purchase terms Use the same purchase type; include delivery charges and subscription conditions.
Review testing information Match any certificate or test report to the specific product and lot.

FDA’s supplement guidance explains required label information and recommends discussing supplement use with a healthcare professional. A manufacturer’s ingredient list is evidence of what it declares, not proof of a personal health result.

Frequently Asked Questions

Which brands should I compare after menopause?

Start with the category you need to understand: HMB combinations, bone-related nutrients, a multivitamin, protein powder, or collagen. The eight brands above provide examples across those categories. Review an individual product’s label and suitability rather than choosing by brand name alone.

Does every woman after menopause need calcium and vitamin D supplements?

A product comparison cannot determine your personal need. Review food intake, medicines, and any relevant health information with your healthcare professional before adding a supplement.

Can I combine AgelessLX with a multivitamin?

[Sponsored] Compare the complete labels first. AgelessLX includes vitamins and minerals that may overlap with a multivitamin or separate supplements. Bring both labels to your healthcare professional rather than assuming they should be combined.

What should I know about biotin and blood tests?

Biotin can interfere with certain laboratory tests. Tell your healthcare professional and laboratory staff about biotin-containing supplements before testing. See NIH’s biotin guidance.

What should someone taking warfarin check?

Vitamin K can interact with warfarin. Discuss changes to vitamin K-containing supplements with your prescriber, including products with K1 or K2. NIH’s vitamin K guidance explains the importance of consistent intake.

Does ingredient research establish the results of a complete formula?

Ingredient research must be considered in the context of the formula, dose, participants, and outcomes studied. Label information alone does not show what results a supplement will produce.

Make a Shortlist You Can Review

Choose the relevant product category, compare two or three complete labels within that category, and check for overlap with what you already take. Use the comparison to prepare a clear discussion with your healthcare professional.

[Sponsored] For AgelessLX, start with the Strawberry Lemonade product page or the capsule product page, then use the label guide to review the serving and precaution details.

Important Information

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

This article provides general product information and is not medical advice. Consult a qualified healthcare professional before starting a supplement, especially if you take medication or have a medical condition.

*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.